{"id":2079,"date":"2026-02-13T16:00:17","date_gmt":"2026-02-13T07:00:17","guid":{"rendered":"https:\/\/riss.aist.go.jp\/nanosafety\/?page_id=2079"},"modified":"2026-02-13T16:07:54","modified_gmt":"2026-02-13T07:07:54","slug":"seika","status":"publish","type":"page","link":"https:\/\/riss.aist.go.jp\/nanosafety\/cnf\/seika\/","title":{"rendered":"\u6210\u679c\u8ad6\u6587\u7b49\u30ea\u30b9\u30c8"},"content":{"rendered":"\n

\u8ad6\u6587<\/strong><\/h3>\n\n\n\n

\u6392\u51fa\u30fb\u66b4\u9732\u8a55\u4fa1<\/strong><\/p>\n\n\n\n

    \n
  1. Ogura I, Kotake M. Dustiness and aerosol characteristics of nanocellulose powders: Implications for workplace exposure and safety management. NanoImpact 2026, 41: 100610. LINK<\/a><\/li>\n\n\n\n
  2. Ogura I, Kotake M, Kuboyama T, Kajihara H. Measurements of cellulose nanofiber emissions and potential exposures at a production facility. NanoImpact 2020, 20:100273. LINK<\/a><\/li>\n<\/ol>\n\n\n\n

    \u6709\u5bb3\u6027\u8a55\u4fa1<\/strong><\/p>\n\n\n\n

      \n
    1. Fujita K, Obara S, Maru J, Kawai Y, Endoh S, Moriyama A. Pulmonary inflammation and immune responses induced by nanocellulose: Insights fromin vivo<\/em> and in vitro<\/em> models. Curr Res Toxicol. 2025, 100259. LINK<\/a><\/li>\n\n\n\n
    2. Fujita K and Moriyama A. Inhalation toxicity of cellulose nanofibrils: A review of key findings and future directions. Carbohydr. Polym. Technol. Appl. 2025, 11:100913. LINK<\/a><\/li>\n\n\n\n
    3. Horie M, Sugino S, Fujita K, Endoh S, Maru J, Matsuzawa T, Ogura I. Evaluation of inflammatory and mesothelioma-related responses in mice following the intraperitoneal administration of cellulose nanofibers. NanoImpact. 2025 10(38):100561. LINK<\/a><\/li>\n\n\n\n
    4. Fujita K, Obara S, Maru J, Kawai Y, Endoh S. Pulmonary inflammatory responses and retention dynamics of cellulose nanofibrils. Toxicology. 2025, 511:154038. LINK<\/a><\/li>\n\n\n\n
    5. Fujita K, Obara S, Maru J, Endoh S, Kawai Y, Moriyama A, Horie M. Assessing cytotoxicity and biocompatibility of cellulose nanofibrils on alveolar macrophages. Cellulose. 2024, 32:241\u2013260. LINK<\/a><\/li>\n\n\n\n
    6. \u85e4\u7530\u514b\u82f1\u3001\u30bb\u30eb\u30ed\u30fc\u30b9\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306e\u5438\u5165\u6bd2\u6027\u8a55\u4fa1\u3001\u30aa\u30ec\u30aa\u30b5\u30a4\u30a8\u30f3\u30b9 2024, 24(5): 197\u2013203. LINK<\/a><\/li>\n\n\n\n
    7. Fujita K, Obara S, Maru J, Endoh S. Effects of advanced nanomaterials on the respiratory system of a murine COPD model. Toxicology Reports. 2023, 11:481\u2013492. LINK<\/a><\/li>\n\n\n\n
    8. Horie M, Fujita K, Endoh S, Sugino S, Maru J, Moriyama A, Ogura I. Contaminant microorganisms in the in vitro evaluation of cellular responses of cellulose nanofibers and their microbial inactivation using gamma irradiation. Toxicol Mech Methods. 2023, 33(9):741\u2013754. LINK<\/a><\/li>\n\n\n\n
    9. Moriyama A, Ogura I, Fujita K. Potential issues specific to cytotoxicity tests of cellulose nanofibrils. J Appl Toxicol. 2023, 43(1):195\u2013207. LINK<\/a><\/li>\n\n\n\n
    10. Fujita K, Obara S, Maru J, Endoh S. Genotoxicity assessment of cellulose nanofibrils using a standard battery of in vitro<\/em> and in vivo <\/em>assays. <\/em>Toxicology Reports. 2022, 9:68\u201377. LINK<\/a><\/li>\n\n\n\n
    11. Fujita K, Obara S, Maru J, Endoh S. Pulmonary inflammation following intratracheal instillation of cellulose nanofibrils in rats: comparison with multi-walled carbon nanotubes. Cellulose. 2021, 28:7143\u20137164. LINK<\/a><\/li>\n\n\n\n
    12. Sai T, Maru J, Obara S, Endoh S, Kajihara H, Fujita K. Screening of preservatives and evaluation of sterilized cellulose nanofibers for toxicity studies. J Occup Health. 2020, 62(1):e12176. LINK<\/a><\/li>\n\n\n\n
    13. Sai T and Fujita K, A review of pulmonary toxicity studies of nanocellulose. Inhal Toxicol. 2020, 32(6):231\u2013239. LINK<\/a><\/li>\n<\/ol>\n\n\n\n

      \u751f\u614b\u5f71\u97ff\u8a55\u4fa1<\/strong><\/p>\n\n\n\n

        \n
      1. Mano H, Tai R, Moriyama A, Iizumi Y, Matsuzawa T, Okazaki T, Ogura I. Dilution effect of TEMPO-oxidized cellulose nanofibers on reproduction of Daphnia<\/em> magna<\/em>. Ecotoxicol Environ Saf. 2025 1;294:118101. LINK<\/a><\/li>\n\n\n\n
      2. Tai R, Ogura I, Okazaki T, Iizumi Y, Mano H. Algal growth inhibition test with TEMPO-oxidized cellulose nanofibers. NanoImpact 2024, 34, 100504. LINK<\/a><\/li>\n\n\n\n
      3. Tai R, Ogura I, Okazaki T, Iizumi Y, Mano H. Acute toxicity tests of TEMPO-oxidized cellulose nanofiber using Daphnia<\/em> magna<\/em> and Oryzias<\/em> latipes<\/em>. Cellulose 2024, 31, 2207\u20132220. LINK<\/a><\/li>\n\n\n\n
      4. \u7530\u4e95\u68a8\u7d75\u3001\u5c0f\u5009\u52c7\u3001\u771e\u91ce\u6d69\u884c\u3001\u30bb\u30eb\u30ed\u30fc\u30b9\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306e\u751f\u614b\u6bd2\u6027\u8a66\u9a13\u624b\u6cd5\u306e\u73fe\u72b6\u3068\u7559\u610f\u70b9\u3001\u74b0\u5883\u6bd2\u6027\u5b66\u4f1a\u8a8c 2022, 25:32\u201347. LINK<\/a><\/li>\n<\/ol>\n\n\n\n

        \u7dcf\u8aac\u30fb\u89e3\u8aac<\/strong><\/h3>\n\n\n\n

        <\/p>\n\n\n\n

          \n
        1. \u5c0f\u5009 \u52c7\u3001\u85e4\u7530 \u514b\u82f1\u3001\u5800\u6c5f \u7950\u7bc4\u3001\u68ee\u5c71 \u7ae0\u5f18\u3001\u7530\u4e95 \u68a8\u7d75\u3001\u771e\u91ce \u6d69\u884c\u3001\u30bb\u30eb\u30ed\u30fc\u30b9\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306e\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3001\u6210\u578b\u52a0\u5de5 2023, 35(4): 122\u2013125. LINK<\/a><\/li>\n\n\n\n
        2. \u85e4\u7530\u514b\u82f1\u3001\u68b6\u539f\u79c0\u592b\u3001\u5c0f\u5009\u52c7\u3001CNF\u306e\u5b89\u5168\u6027\u8a55\u4fa1\u624b\u6cd5\u306e\u958b\u767a\u3068\u8a55\u4fa1\u4e8b\u4f8b\uff5e\u5438\u5165\u6bd2\u6027\u3001\u907a\u4f1d\u6bd2\u6027\u3001\u751f\u5206\u89e3\u6027\uff5e\u3001\u5bb9\u5668\u5305\u88c5\u6750\u6599\u306e\u74b0\u5883\u5bfe\u5fdc\u3068\u30ea\u30b5\u30a4\u30af\u30eb\u6280\u8853\u3001\u6280\u8853\u60c5\u5831\u5354\u4f1a 2022, 475\u2013481. LINK<\/a><\/li>\n\n\n\n
        3. \u5c0f\u5009\u52c7\u3001\u85e4\u7530\u514b\u82f1\u3001\u5c0f\u6817\u670b\u5b50\u3001\u68b6\u539f\u79c0\u592b\u3001NEDO\u59d4\u8a17\u4e8b\u696d\u300cCNF\u306e\u5b89\u5168\u6027\u8a55\u4fa1\u624b\u6cd5\u306e\u958b\u767a\u300d\u306e\u6210\u679c\u3001\u30bb\u30eb\u30ed\u30fc\u30b9\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc \u7814\u7a76\u3068\u5b9f\u7528\u5316\u306e\u6700\u524d\u7dda\uff08\u76e3\u4fee\uff1a\u77e2\u91ce\u6d69\u4e4b\u3001\u78ef\u8c9d\u660e\u3001\u5317\u5ddd\u548c\u7537\uff09\u3001\u30a8\u30cc\u30fb\u30c6\u30a3\u30fc\u30fb\u30a8\u30b9 2021, 379\u2013386. LINK<\/a><\/li>\n\n\n\n
        4. \u5c0f\u5009\u52c7\u3001\u85e4\u7530\u514b\u82f1\u3001\u5c0f\u6817\u670b\u5b50\u3001\u84b2\u751f\u660c\u5fd7\u3001\u68b6\u539f\u79c0\u592b\u3001\u30bb\u30eb\u30ed\u30fc\u30b9\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306e\u5b89\u5168\u6027\u306b\u3064\u3044\u3066\u3001\u5de5\u696d\u6750\u6599 2020, 68(8): 20\u201323. LINK<\/a><\/li>\n<\/ol>\n\n\n\n

          <\/p>\n","protected":false},"excerpt":{"rendered":"

          \u8ad6\u6587 \u6392\u51fa\u30fb\u66b4\u9732\u8a55\u4fa1 \u6709\u5bb3\u6027\u8a55\u4fa1 \u751f\u614b\u5f71\u97ff\u8a55\u4fa1 \u7dcf\u8aac\u30fb\u89e3\u8aac<\/p>\n","protected":false},"author":19,"featured_media":0,"parent":1110,"menu_order":6,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2079","page","type-page","status-publish","hentry"],"aioseo_notices":[],"acf":[],"_links":{"self":[{"href":"https:\/\/riss.aist.go.jp\/nanosafety\/wp-json\/wp\/v2\/pages\/2079","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/riss.aist.go.jp\/nanosafety\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/riss.aist.go.jp\/nanosafety\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/riss.aist.go.jp\/nanosafety\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"https:\/\/riss.aist.go.jp\/nanosafety\/wp-json\/wp\/v2\/comments?post=2079"}],"version-history":[{"count":4,"href":"https:\/\/riss.aist.go.jp\/nanosafety\/wp-json\/wp\/v2\/pages\/2079\/revisions"}],"predecessor-version":[{"id":2084,"href":"https:\/\/riss.aist.go.jp\/nanosafety\/wp-json\/wp\/v2\/pages\/2079\/revisions\/2084"}],"up":[{"embeddable":true,"href":"https:\/\/riss.aist.go.jp\/nanosafety\/wp-json\/wp\/v2\/pages\/1110"}],"wp:attachment":[{"href":"https:\/\/riss.aist.go.jp\/nanosafety\/wp-json\/wp\/v2\/media?parent=2079"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}