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\u7523\u7dcf\u7814\u306e\u7814\u7a76\u6210\u679c\u3068\u3057\u3066\u3001\u201cPulmonary inflammation and immune responses induced by nanocellulose: Insights from in vivo<\/em> and in vitro<\/em> models\u201d\u3068\u984c\u3057\u305f\u7814\u7a76\u8ad6\u6587\u304c\u3001Current Research in Toxicology\uff08Elsevier\uff09\u306b\u304a\u3044\u30662025\u5e749\u670825\u65e5\u4ed8\u3051\u3067\u767a\u884c\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

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\u3059\u3079\u3066\u306e\u6750\u6599\u306f2.0 mg\/kg\u3067\u6295\u4e0e\u3055\u308c\u300128\u65e5\u5f8c\u306b\u306f\u5168\u3066\u306eNC\u304c\u80ba\u80de\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306b\u8caa\u98df\u3055\u308c\u307e\u3057\u305f\u3002CNF1\u3068CNC1\u306f\u708e\u75c7\u6027\u30de\u30fc\u30ab\u30fc\u306b\u5909\u5316\u3092\u793a\u3057\u3001CNC1\u306f\u6700\u3082\u9855\u8457\u306a\u7d44\u7e54\u5909\u5316\u3092\u793a\u3057\u307e\u3057\u305f\u3002CNF2\u306f\u9650\u5c40\u7684\u306a\u708e\u75c7\u3068\u8089\u82bd\u816b\u5f62\u6210\u3092\u793a\u3057\u3001BALF\u306e\u5909\u5316\u306f\u6700\u5c0f\u9650\u3067\u3057\u305f\u3002\u3044\u305a\u308c\u306eNC\u3082MWCNT\u3088\u308a\u708e\u75c7\u53cd\u5fdc\u304a\u3088\u3073\u7d44\u7e54\u5909\u5316\u304c\u8efd\u5ea6\u3067\u3057\u305f\u3002\u813e\u81d3\u30fb\u80f8\u817a\u306e\u30ea\u30f3\u30d1\u7403\u30b5\u30d6\u30bb\u30c3\u30c8\u306b\u6709\u610f\u306a\u5909\u5316\u306f\u8a8d\u3081\u3089\u308c\u305a\u3001\u5168\u8eab\u6027\u514d\u75ab\u6bd2\u6027\u306f\u78ba\u8a8d\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n

in vitro<\/em>\u8a66\u9a13\u3067\u306f\u3001CNC1\u3001CNC2\uff08\u786b\u9178\u52a0\u6c34\u5206\u89e3\uff09\u3001CNC3\uff08\u8131\u786b\uff09\u3092\u6bd4\u8f03\u3057\u305f\u7d50\u679c\u3001\u5168\u3066\u306eCNC\u304c\u30e9\u30c3\u30c8\u80ba\u80de\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\uff08NR8383\uff09\u306b\u53d6\u308a\u8fbc\u307e\u308c\u3001\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u7523\u751f\u304c\u5897\u52a0\u3057\u307e\u3057\u305f\u3002\u53cd\u5fdc\u306f\u8868\u9762\u5316\u5b66\u306b\u3088\u308a\u7570\u306a\u308a\u3001CNC3\u306f\u8efd\u5ea6\u301c\u4e2d\u7b49\u5ea6\u306e\u7d30\u80de\u6bd2\u6027\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u3053\u308c\u3089\u306e\u7d50\u679c\u304b\u3089\u3001NC\u306f\u4e00\u822c\u306bMWCNT\u3088\u308a\u3082\u80ba\u6bd2\u6027\u304c\u4f4e\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u304c\u3001\u305d\u306e\u751f\u7269\u5b66\u7684\u5f71\u97ff\u306f\u7e4a\u7dad\u5f62\u614b\u3001\u8868\u9762\u7279\u6027\u3001\u80ba\u5185\u3067\u306e\u6c88\u7740\u6319\u52d5\u306b\u3088\u308a\u5927\u304d\u304f\u5de6\u53f3\u3055\u308c\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u308a\u307e\u3057\u305f\u3002NC\u306e\u5b89\u5168\u306a\u5229\u7528\u306b\u306f\u3001\u6df7\u5165\u5fae\u751f\u7269\u3084\u30a8\u30f3\u30c9\u30c8\u30ad\u30b7\u30f3\u306e\u53b3\u5bc6\u306a\u691c\u67fb\u3068\u7ba1\u7406\u3092\u542b\u3081\u3001\u6750\u6599\u7279\u6027\u306b\u5fdc\u3058\u305f\u5305\u62ec\u7684\u306a\u6bd2\u6027\u8a55\u4fa1\u3068\u6a19\u6e96\u5316\u3055\u308c\u305f\u8a55\u4fa1\u67a0\u7d44\u307f\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/p>\n\n\n

\n
\"\"<\/a><\/figure>\n<\/div>\n\n\n

<\/p>\n\n\n\n

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\u30ea\u30f3\u30af<\/p>\n\n\n\n

https:\/\/doi.org\/10.1016\/j.crtox.2025.100259<\/a><\/p>\n\n\n\n

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\uff08\u6587\u8cac\uff1a\u85e4\u7530\u514b\u82f1\uff09<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

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